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Wednesday, August 20, 2014

Faulty Body Clock Genes May Be Responsible for Bipolar

Sorry for the long wait hear my new post after all this wait.

So a malfunctioning circadian clock genes may be responsible for bipolar.

Researchers writing in the open access journal BMC Psychiatry found four versions of a regulatory gene RORB that were associated with bipolar.

Alexander Niculescu from Indiana University School of Medicine worked with a team of researchers at Harvard, UC San Diego, Massachusetts General Hospital and SUNY Upstate Medical University to study the RoRA and RoRB genes of 152 kids with bipolar and 140 control children. They found four alterations to the RORB gene that was link to bipolar.

According to Niculescu, "Bipolar disorder is often characterized by circadian rhythm abnormalities.

Decreased sleep has even been noted as one of the earliest symptoms discriminating children with bipolar disorder from those with attention deficit hyperactivity disorder

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